Bioscience

Study shows hypomethylation can increase progression of multiple myeloma

October 4, 2010

By Flinn Foundation

[Source: The Medical News] – DNA methylation — a modification of DNA linked to gene regulation — is altered with increasing severity in a blood cancer called multiple myeloma, according to a study by Mayo Clinic and the Translational Genomics Research Institute (TGen).

And at specific points of DNA, “global hypomethylation,” in which many genes lose the modification, may be associated with the step-by-step development of myeloma, according to a scientific paper published this month in the journal Cancer Research.

For more information: Study shows hypomethylation can increase progression of multiple myeloma