Bioscience

Hormone replacement may not save women’s muscle

August 22, 2010

By Flinn Foundation

[Source: World Bulletin] – Despite some earlier evidence that hormone replacement therapy after menopause can help maintain women’s muscle mass, a new study suggests that any such benefit does not last.

That women’s muscle mass declines after menopause has long been known, and researchers have speculated that waning estrogen levels may play a role — raising the question of whether hormone replacement therapy (HRT) can help preserve older women’s muscle mass.

Results from the Women’s Health Initiative (WHI), a large U.S. clinical trial looking at a variety of health effects of HRT, found that women who used hormones for three years maintained somewhat more muscle mass than those who had been given a placebo for comparison.

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