Bioscience

C-Path researchers crack diseases through math, info sharing

March 14, 2009

By Flinn Foundation

Source: Nicholas Smith, Inside Tucson Business] – Mention clinical pharmacology to someone and they’ll probably get an image of lab coats and test tubes, but that’s not quite Klaus Romero’s job description.

His role as a clinical pharmacologist for the Critical Path Institute revolves more around math equations and trend lines.

“The idea is that those models should have practical applications for the drug development process,” he said.

Romero begins by taking all the data he can find on diseases like polycystic renal disease, which can lead to kidney failure, to find a mathematical model that represents the common points of the disease. These equations can be used to determine which patients have a good chance of benefitting from which drugs.

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