Bioscience

Hospitals may unite pediatric divisions

Pressured by revenue cuts, Phoenix Children's Hospital and St. Joseph's Hospital and Medical Center have entered talks about combining their pediatric units.

Senior executives of the two central-Phoenix hospitals emphasized that nothing has been decided but that discussions are moving along.

Lacosamide validated as promising therapy for uncontrolled partial-onset seizures

A recent multi-center study has confirmed earlier study results that 400 mg/day of lacosamide provides a good balance of efficacy and tolerability for patients with uncontrolled partial-onset seizures (POS), and doses of 600mg/day may provide additional benefit for some patients. Researchers from the Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Thomas Jefferson University Medical School, Arkansas Epilepsy Program, Schwarz Biosciences and Johns Hopkins University Hospital conducted this study which is available early online in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy.

Medical clinical trials face obstacles

Scientific researchers in the Valley have high hopes for new therapies for patients with certain types of cancer.

New drugs are constantly in development at the Translational Genomics Research Institute, also known as TGen, based in Phoenix. But some of the clinical trials to test these new drugs could be at risk if more cancer patients don’t get involved in the studies.

In collaboration with the Virginia G. Piper Cancer Center at Scottsdale Healthcare, TGen has about 35 clinical trials under way. These trials test the safety and effectiveness of the new drugs prior to approval by the U.S. Food and Drug Administration.

SBS will hold its 16th annual conference & exhibition in Phoenix

[Source: SBS] - On April 11, more than 2,000 scientists, researchers and industry leaders from around the world will converge in Phoenix for the SBS 16th Annual Conference & Exhibition, Advancing the Science of Drug Discovery.

This five-day event will be held at the Phoenix Convention Center and will feature keynote addresses from acclaimed scientists, with topics ranging including: lead discovery in immunoinflammation; lead discovery in oncology, critical reagents; lead discovery in neurosciences; epigenetics; and assays & automation.

 

The conference will also include feature presentations, short courses, and workshops emphasizing the growing integration of the biomolecular sciences and their influence on drug research and development. SBS will highlight the most significant and exciting recent advances in the cutting-edge science that underpins the discovery and development of new medicines.

 

In the exhibit hall, some 150 bio-technology innovators will provide breaking news, demonstrations of emerging technologies, tutorials, new products and services, poster presentations and interactive discussion sessions. This annual event provides scientists and life science executives the opportunity to network with peers, share best practices and present their own research in drug discovery. For more information on the SBS conference, please visit www.sbsonline.org/conference . 

Natural antioxidants give top barn swallows a leg on competitors

The study is the first to track concentrations of carotenoids, which are naturally occurring plant pigments, in a wild bird or animal species over the course of the grueling breeding season. Carotenoids can offer the benefits associated with over-the-counter nutritional supplements that protect cells from free radical damage, said CU-Boulder Assistant Professor Rebecca Safran.

Mayo Clinic responsible for $1.5B economic impact in Arizona

Mayo Clinic is responsible for $1.5 billion in economic impact in Arizona, according to data from a study conducted by the Battelle Memorial Institute. Mayo generates more than $747 million in direct economic output in Arizona, and this spending leads to more than $700 million in additional economic output.

In terms of job creation, Mayo Clinic overall employs more than 57,000 people, including 10,600 in Arizona. In Arizona, Mayo employs 4,651 full-time workers and supports an additional 5,964 jobs, resulting in employment for more than 10,000 people.

The study shows that Mayo Clinic, as a three-site organization, (Arizona, Florida and Minnesota) is responsible for $22 billion in economic impact nationwide.

Intel, partners to give $3.5 billion to tech startups

Intel Corp.'s plans to direct $3.5 billion of investments into U.S. technology companies could help cash-strapped startups in Arizona, where venture-capital activity is lagging.

The Santa Clara, Calif.-based semiconductor giant said Tuesday that its venture-capital arm, Intel Capital, was forming a $200 million fund to focus on domestic companies developing "clean" technology, information technology
 and biotech.

SBS will hold its 16th annual conference & exhibition in Phoenix

On April 11, more than 2,000 scientists, researchers and industry leaders from around the world will converge in Phoenix for the SBS 16th Annual Conference & Exhibition, Advancing the Science of Drug Discovery.

Researchers find oncogene is important in pancreatic cancer growth and spread

Researchers at the Mayo Clinic campus in Florida have found that PKC-iota (PKCi), an oncogene important in colon and lung cancers, is over-produced in pancreatic cancer and is linked to poor patient survival. They also found that genetically inhibiting PKCi in laboratory animals led to a significant decrease in pancreatic tumor growth and spread.

The discovery, reported in the March 1 issue of Cancer Research, is especially encouraging, they say, because an experimental agent that targets PKCi is already being tested in patients at Mayo Clinic.

Aphid’s genome reflects its reproductive, symbiotic lifestyle

Aphids could be considered the "mosquitoes" of the plant world, depending on the "blood" of plants to survive. They live in symbiosis with bacteria that pass from one generation to the next, producing essential amino acids. Aphids with the same genotype can be wingless or winged. In different seasons, they develop as asexual females who produce offspring with identical genes through parthenogenesis. When temperatures drop, they can give birth to males who then fertilize the eggs laid by females.

The genome of the pea aphid, sequenced by the International Aphid Genomics Consortium, reflects these unusual characteristics and more, said Dr. Stephen Richards, assistant professor in the Baylor College of Medicine Human Genome Sequencing Center and leader of the sequencing effort. The consortium released the 464 megabyte draft genome of the pea aphid (Acyrthosiphon pisum) in the current issue of PLoS Biology.

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